Gorlin-Goltz Syndrome

Abstract

Gorlin-Goltz syndrome is a rare autosomal dominant disorder. It is associated with many phenotypic abnormalities, which can be classified into developmental anomalies and postnatal tumors, especially basal cell carcinomas. In most cases, it manifests early in life or near puberty. The case is presented of a 38-year-old female patient, of white skin color and without disease history, who was received at the dermatology office of Hospital Docente Clínico Quirúrgico Dr. Joaquín Albarrán Domínguez, in Havana, in December 2022, due to the presence of multiple skin lesions on her face, thorax, back and arms, as well as palmar depressions, mild hypertelorism and coarse face. A skin biopsy of one of the lesions showed basal cell nevus. Skull x-rays showed calcification of the brain sickle and odontogenic cysts. It is concluded as Gorlin-Goltz syndrome. The case is presented due to the rarity of this disease in our setting, as well as for its importance.